Slay the Spire 2 Relic Tier List

Every relic ranked from game-changing S-tier picks to highly situational D-tier options. Evaluated for general use across the full roster.

Card Tier List Potions Tier List

⚠️ Slay the Spire 2 is in Early Access (launched March 2026). This tier list reflects the current build and will be updated as balance patches roll out.

METHODOLOGY

S-Tier: The best of the best. These Relics are highly sought after regardless of the archetype you're playing, and can generally be taken at any time. A-Tier: Only a slight step down from S-Tier. These Relics are powerful across many situations and may require minimal synergy. B-Tier: The bread and butter pickups that will serve you well in almost all runs. While not the cream of the crop, they're flexible and reliable. C-Tier: Good relics that require more synergy to shine than those in B-Tier. Worth considering in the right build. D-Tier: Highly situational or below the average rate. Low impact relics that may even hinder more than help in general runs. Note: Relics are judged on general usage across the entire roster. Ancient and Starter relics are not included.